Assessing the location and stability of electrical rotors can help target ablation therapy for atrial fibrillation. Rotor cores can be tracked by identifying singularities in the phase of spatially distributed electrical recordings. This is routinely applied to unipolar electrogram and action potential data, but not to bipolar electrogram data, which contains local activation only. We […]
Spectral/hp element methods and an arbitrary Lagrangian-Eulerian (ALE) moving-boundary technique are used to investigate planar Newtonian extrudate swell. Newtonian extrudate swell arises when viscous liquids exit long die slits. The problem is characterised by a stress singularity at the end of the slit which is inherently difficult to capture and strongly influences the predicted swelling […]
Developing software to undertake complex, compute-intensive scientific processes requires a challenging combination of both specialist domain knowledge and software development skills to convert this knowledge into efficient code. As computational platforms become increasingly heterogeneous and newer types of platform such as Infrastructure-as-a-Service (IaaS) cloud computing become more widely accepted for HPC computations, scientists require more […]
When treating atrial arrhythmias using catheter ablation it is standard practice to create local activation maps of a patient’s atrium to guide treatment. Generating these maps involves recording hundreds of electrograms from the inside surface of the chamber and then using automated algorithms to identify deflections in the signal and choose the activation time for […]
Electroanatomic mapping systems collect increasingly large quantities of spatially-distributed electrical data which may be potentially further scrutinized post-operatively to expose mechanistic properties which sustain and perpetuate atrial fibrillation. We describe a modular software platform, developed to post-process and rapidly analyse data exported from electroanatomic mapping systems using a range of existing and novel algorithms. Imaging […]
Determining locations of focal arrhythmia sources and quantifying myocardial conduction velocity (CV) are two major challenges in clinical catheter ablation cases. CV, wavefront direction and focal source location can be estimated from multipolar catheter data, but currently available methods are time-consuming, limited to specific electrode configurations, and can be inaccurate. We developed automated algorithms to […]